What does Error mean - Error Code run out of filament but new spool in place

UP300 stopped feeding the PLA filament through. I have removed and cleaned the nozzle and filament feed “cog” both of which had some mild debris (not excessive). Printer will only print a few lines before I get an error that I have run out of filament. The filament is a new type ( PLA with Graphene) however it is able to extrude through the nozzle. In addition to the “run out of filament error” I am now getting an error code What does this mean?
Anyone know how to fix this?